AACT Pre-Meeting Symposium


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AACT Pre-Symposium: Cardiotoxins: An in-depth look at the Pathophysiology, Presentation, and Management of Heart Poisoning

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AACT Pre-Symposium: Cardiotoxins: An in-depth look at the Pathophysiology, Presentation, and Management of Heart Poisoning

Oct 12, 2017 8:00am ‐ Oct 12, 2017 12:00pm

Alex Manini, MD
The Potassium Channel
Learning Objectives:

  1. Understand how toxins modify the cardiac action potential by interference with potassium channels
  2. Discuss how certain ECG findings dictate management of the poisoned patient

Jason Chu, MD
The Calcium Channel
Learning Objective:

  1. Describe the pathophysiology of L-type and ryanodine receptors blockade and targeted therapies to reverse toxicity

Robert S. Hoffman, MD
Pathophysiology of Gap Junctions and QRS Prolongation
Learning Objectives:

  1. Explain the role that different junctions serve in cellular communication
  2. Compare conductance through the gap junction with traditional sodium channels and voltage dependent calcium channels

James Cao, MD
Coronary Artery Disease

Learning Objectives:

  1. Review toxicologic causes of acute coronary syndrome
  2. Discuss the evidence associating cocaine with acute coronary syndrome

Kristen Engebretsen, PharmD
Debate: HDI vs Vasopressors
Learning Objectives:

  1. Discuss the data supporting the use of insulin or vasopressors in toxin induced cardiovascular shock
  2. Identify the differences between animal data and human data supporting the use of HIE in toxin induced CV shock

Samuel Stellpflug, MD
Debate: HDI vs Vasopressors
Learning Objectives:

  1. Compare the the use of insulin to vasopressors for treatment of calcium channel blocker poisoning

Michael Levine, MD
Debate: HDI vs Vasopressors
Learning Objectives:

  1. Understand the rationale for the use of vasopressors in the treatment of calcium channel blocker overdose
  2. Discuss why one may choose vasopressors over high dose insulin

Meghan Spyres, MD
Debate: HDI vs Vasopressors

Speaker(s): Speaker(s):

AACT Pre-Symposium: Cardiotoxins: An in-depth look at the Pathophysiology, Presentation, and Management of Heart Poisoning

Preview Available

AACT Pre-Symposium: Cardiotoxins: An in-depth look at the Pathophysiology, Presentation, and Management of Heart Poisoning

Oct 12, 2017 1:00pm ‐ Oct 12, 2017 5:00pm

Philippe Hantsone, MD, MPH
Drug-Induced Cardiomyopathy (more chronic)
Learning Objectives:

  1. Discuss the pathophysiology of ernegetic failure in drug-induce cardiomyopathy
  2. Understand the role of metabolic therapies versus cardiotropic drugs

Tammi Schaeffer, DO
Durg-Induced Takotsubo Cardiomyopathy
Learning Objectives:

  1. Discuss the epidemiology and pathophysiology of drug-induced Takotsubo's cardiomyopathy
  2. Discuss the clinical presentation and treatment of drug-induced Takotsubo's cardiomyopathy

Sophie Gosselin, MD
Natural Cardiotoxins
Learning Objectives:

  1. Describe the pathophysiology of various cardiotoxins encountered in nature and their broad classification
  2. Recognize the clinical patterns of potential natural cardiotoxins to formulate a treatment strategy

Ben Hatten, MD, MPH
Central Alpha-2 Agonists
Learning Objectives:

  1. Describe the receptor interactions in cases of alpha-2 agonist exposure
  2. Describe the clinical syndrome associated with alpha-2 agonist toxicity

Marco Sivilotti, MD
Panel: Debate: Ethics of Using Antidotes With No Quality Human Date
Learning Objective:

  1. Discuss possible approaches to informing patients of treatment options when there are no high quality studies on the disease

Craig Smollin, MD
Panel: Ethics of Using Antidotes with No Quality Human Data

Jeffrey Brent, MD, PhD
Panel: Debate: Ethics of Using Antidotes With No Quality Human Date


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