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Mini-symposium: Acetaminophen Poisoning


May 29, 2013 11:20am ‐ May 29, 2013 12:45pm


Credits: None available.

Description

Learning Objectives:

  • Can you describe the epidemiology of paracetamol poisoning in the UK
  • Can you identify the adverse effects of acetylcysteine when managing paracetamol overdose
  • Can you give examples of the challenges in design and conduct of a controlled randomized clinical trial in paracetamol poisoning
  • Can you outline the pharmacokinetics of acetylcysteine in man and the implications for IV dosing regimens
  • Can you describe the primary and secondary objectives within a clinical trial methodology, and evaluate whether ondansetron is effective in preventing acetylcysteine-induced nausea and vomiting
  • Can you list biomarkers that detect acute liver injury from paracetamol at first presentation
  • Can you compare and contrast the strengths and weaknesses of these biomarkers
  • Can you apply how these biomarkers may be used in your clinical practice
  • Can you describe the use of acetylcysteine in paracetamol overdose in different parts of the world
  • Can you discuss recent changes in the use of acetylcysteine in paracetamol overdose in the UK

Speaker(s):

Speaker(s):

Credits

Credits: None available.

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