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Symposium: New Insights in Mechanisms of Toxicity and Their Clinical Relevance - Part 1


May 29, 2014 2:00pm ‐ May 29, 2014 3:30pm


Credits: None available.

Description

Objectives:

  • Can you discuss how epigenetic modulation allows long-term regulation of gene activity and how it explains the long-term effects of toxic agents?
  • Can you describe the strengths and weaknesses of microRNA as toxicity biomarkers in blood and urine?
  • Can you describe the basic mechanistic work that has shown that diglycolic acid is the nephrotoxic metabolite of diethylene glycol poisoning?
  • Can you describe the molecular action of DNA alkylating agents e.g. sulfur mustard and link it to the clinical picture?

Speaker(s):

Speaker(s):

Credits

Credits: None available.

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