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Utility of Experimental Data in Poisons Information and Patient Management - Part 1


May 28, 2015 9:45am ‐ May 28, 2015 10:30am


Credits: None available.

Description

Learning Objectives:

  • Explain the current paradigm shift in safety testing away from standard animal experiments towards understanding of toxicity pathways in the context of human exposure.
  • Recognize the differences between mechanism of action, mode of action and adverse outcome pathways and their uses in risk assessment.
  • Describe how emerging concepts such as systems toxicology and the human exposome will change the face of health risk assessment.
  • Discuss existing in vitro lung cell culture models and their use in toxicological and pharmacological experiments.
  • Discuss the advantages but also limitations of these models with regard to the experimental data derived thereof.
  • Discuss ongoing research to improve existing models and techniques in order to meet regulatory requirements

Speaker(s):

Speaker(s):

Credits

Credits: None available.

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